Readily Accessible Bulky Iron Catalysts exhibiting Site Selectivity in the Oxidation of Steroidal Substrates
dc.contributor.author
dc.date.accessioned
2016-06-08T08:28:01Z
dc.date.available
2016-06-08T08:28:01Z
dc.date.issued
2016
dc.identifier.issn
1433-7851
dc.identifier.uri
dc.description
El mateix article està publicat a l'edició alemanya d'Angewandte Chemie (ISSN 0044-8249 EISSN:1521-3757), 2016, vol.128, núm. 19, p.5870-5873. DOI http://dx.doi.org/10.1002/ange.201600785
dc.description.abstract
Bulky iron complexes are described that catalyze the site-selective oxidation of alkyl C-H bonds with hydrogen peroxide under mild conditions. Steric bulk at the iron center is introduced by appending trialkylsilyl groups at the meta-position of the pyridines in tetradentate aminopyridine ligands, and this effect translates into high product yields, an enhanced preferential oxidation of secondary over tertiary C-H bonds, and the ability to perform site-selective oxidation of methylenic sites in terpenoid and steroidal substrates. Unprecedented site selective oxidation at C6 and C12 methylenic sites in steroidal substrates is shown to be governed by the chirality of the catalysts
dc.description.sponsorship
Financial support for this work was provided by the European Commission (ERC2009-StG-239910 to M.C.), the Spanish Ministry of Science (CTQ2012-37420-C02-01/BQU to M.C.,
and Generalitat de Catalunya (SGR862 and ICREA Academia Award to M.C.)
dc.format.mimetype
application/pdf
dc.language.iso
eng
dc.publisher
Wiley
dc.relation.isformatof
Reproducció digital del document publicat a: http://dx.doi.org/10.1002/anie.201600785
dc.relation.ispartof
© Angewandte Chemie International Edition, 2016, vol. 55, núm. 19, p. 5776-5779
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Articles publicats (D-Q)
dc.rights
Tots els drets reservats
dc.subject
dc.title
Readily Accessible Bulky Iron Catalysts exhibiting Site Selectivity in the Oxidation of Steroidal Substrates
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/embargoedAccess
dc.embargo.terms
Cap
dc.date.embargoEndDate
info:eu-repo/date/embargoEnd/2026-01-01
dc.relation.projectID
info:eu-repo/grantAgreement/EC/FP7/239910/EU/Bio-inspired Design of Catalysts for Selective Oxidations of C-H and C=C Bonds/BIDECASEOX
dc.type.version
info:eu-repo/semantics/publishedVersion
dc.identifier.doi
dc.identifier.idgrec
024884
dc.relation.FundingProgramme
dc.relation.ProjectAcronym
dc.identifier.eissn
1521-3773