{ "dc.contributor.author": "Marchi Luciano, Hugo" , "dc.contributor.author": "Lledó Ponsati, Agustí" , "dc.date.accessioned": "2025-01-10T12:27:21Z" , "dc.date.available": "2025-01-10T12:27:22Z" , "dc.date.issued": "2025-01-03" , "dc.identifier.issn": "1359-7345" , "dc.identifier.uri": "http://hdl.handle.net/10256/25997" , "dc.description.abstract": "Discrimination of enantiomeric substrate molecules is one of the fundamental properties of biological hosts. Replicating enantioselective molecular recognition with synthetic receptors is a topic of interest with implications in diverse applications such as bioinspired enantioselective catalysis, enantiomer separation, or sensing. In this review, five different systems reported in the literature are discussed, and their performance and versatility are analyzed. A recently reported host featuring a flexible scaffold challenges the long-established view that a high degree of preorganization in combination with strongly directional non-covalent interactions is required for efficient enantiodiscrimination. The review is complemented with an analysis of the synthetic effort required for each of the hosts presented" , "dc.description.sponsorship": "We are grateful for financial support from grants TED2021-130573B-I00, PID2023-146498NB-I00 and REQ2021_B_05 funded by MICIU/AEI/10.13039/501100011033 and by the European Union NextGenerationEU/PRTR. We thank AGAUR/Generalitat de Catalunya for funding (2021SGR623)" , "dc.format.mimetype": "application/pdf" , "dc.language.iso": "eng" , "dc.publisher": "Royal Society of Chemistry (RSC)" , "dc.relation": "TED2021-130573B-I00" , "dc.relation": "PID2023-146498NB-I00" , "dc.relation.isformatof": "Versió postprint del document publicat a: https://doi.org/10.1039/d4cc06107a" , "dc.relation.ispartof": "© Chemical Communications, 2024, vol. undef, núm. undef, p. undef" , "dc.relation.ispartofseries": "Articles publicats (D-Q)" , "dc.rights": "Tots els drets reservats" , "dc.source": "Marchi Luciano, Hugo Lledó Ponsati, Agustí 2024 Chiral synthetic hosts for efficient enantioselective molecular recognition: design principles and synthetic aspects Chemical Communications undef undef undef" , "dc.subject": "Química supramolecular" , "dc.subject": "Quiralitat" , "dc.subject": "Reconeixement molecular" , "dc.subject": "Supramolecular chemistry" , "dc.subject": "Chirality" , "dc.subject": "Molecular recognition" , "dc.subject": "Catàlisi asimètrica" , "dc.subject": "Enantioselective catalysis" , "dc.title": "Chiral synthetic hosts for efficient enantioselective molecular recognition: design principles and synthetic aspects" , "dc.type": "info:eu-repo/semantics/article" , "dc.rights.accessRights": "info:eu-repo/semantics/embargoedAccess" , "dc.embargo.lift": "2026-01-03T00:00:00Z" , "dc.embargo.terms": "2026-01-03T00:00:00Z" , "dc.date.embargoEndDate": "info:eu-repo/date/embargoEnd/2026-01-03" , "dc.relation.projectID": "info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/TED2021-130573B-I00/ES/TECNOLOGÍAS DE QUÍMICA SUPRAMOLECULAR PARA MATERIALES FOTOVOLTAICOS DE NUEVA GENERACIÓN BASADOS EN CARBONO/" , "dc.relation.projectID": "info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2023-146498NB-I00/ES/ESPACIOS CONFINADOS QUIRALES PARA APLICACIONES EN CATALISIS ASIMETRICA Y MATERIALES QUIROPTICOS/" , "dc.type.version": "info:eu-repo/semantics/acceptedVersion" , "dc.identifier.doi": "https://doi.org/10.1039/d4cc06107a" , "dc.identifier.idgrec": "039591" , "dc.contributor.funder": "Agencia Estatal de Investigación" , "dc.type.peerreviewed": "peer reviewed" , "dc.relation.FundingProgramme": "Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023" , "dc.relation.FundingProgramme": "ESPACIOS CONFINADOS QUIRALES PARA APLICACIONES EN CATALISIS ASIMETRICA Y MATERIALES QUIROPTICOS" , "dc.relation.ProjectAcronym": "TECNOLOGÍAS DE QUÍMICA SUPRAMOLECULAR PARA MATERIALES FOTOVOLTAICOS DE NUEVA GENERACIÓN BASADOS EN CARBONO" , "dc.identifier.eissn": "1364-548X" }