{ "dc.contributor.author": "Fernández López, Pol" , "dc.contributor.author": "Garriga, Joan" , "dc.contributor.author": "Casas Roqueta, Isabel" , "dc.contributor.author": "Yeste Oliveras, Marc" , "dc.contributor.author": "Bartumeus Ferré, Frederic" , "dc.date.accessioned": "2022-10-07T10:38:10Z" , "dc.date.available": "2022-10-07T10:38:10Z" , "dc.date.issued": "2022-09-28" , "dc.identifier.issn": "2399-3642" , "dc.identifier.uri": "http://hdl.handle.net/10256/21786" , "dc.description.abstract": "Understanding the organisational principles of sperm motility has both evolutionary and applied impact. The emergence of computer aided systems in this field came with the promise of automated quantification and classification, potentially improving our understanding of the determinants of reproductive success. Yet, nowadays the relationship between sperm variability and fertility remains unclear. Here, we characterize pig sperm motility using t-SNE, an embedding method adequate to study behavioural variability. T-SNE reveals a hierarchical organization of sperm motility across ejaculates and individuals, enabling accurate fertility predictions by means of Bayesian logistic regression. Our results show that sperm motility features, like high-speed and straight-lined motion, correlate positively with fertility and are more relevant than other sources of variability. We propose the combined use of embedding methods with Bayesian inference frameworks in order to achieve a better understanding of the relationship between fertility and sperm motility in animals, including humans" , "dc.description.sponsorship": "This work has been financially supported by grants no. CGL2016-78156-C2- 1-R, AGL2017-88329R, RYC-2014-15581 and PEJ2018-002178-P (Ministry of Science, Spain), and 2017-SGR-1229 (Generalitat de Catalunya, Spain)" , "dc.format.mimetype": "application/pdf" , "dc.language.iso": "eng" , "dc.publisher": "Nature Portfolio" , "dc.relation": "AGL2017-88329-R" , "dc.relation": "RYC-2014-15581" , "dc.relation.isformatof": "Reproducció digital del document publicat a: https://doi.org/10.1038/s42003-022-03954-0" , "dc.relation.ispartof": "Communications Biology, 2022, vol. 5, núm. 1, p. 1027" , "dc.relation.ispartofseries": "Articles publicats (D-B)" , "dc.rights": "Reconeixement 4.0 Internacional" , "dc.rights.uri": "http://creativecommons.org/licenses/by/4.0" , "dc.source": "Fernández López, Pol Garriga, Joan Casas Roqueta, Isabel Yeste Oliveras, Marc Bartumeus Ferré, Frederic 2022 Predicting fertility from sperm motility landscapes Communications Biology 5 1 1027" , "dc.subject": "Espermatozoides -- Motilitat" , "dc.subject": "Spermatozoa -- Motility" , "dc.subject": "Porcs -- Espermatozoides" , "dc.subject": "Swine -- Spermatozoa" , "dc.subject": "Porcs -- Fecunditat" , "dc.subject": "Swine -- Fertility" , "dc.title": "Predicting fertility from sperm motility landscapes" , "dc.type": "info:eu-repo/semantics/article" , "dc.rights.accessRights": "info:eu-repo/semantics/openAccess" , "dc.relation.projectID": "info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2017-88329-R/ES/MEJORA DEL RENDIMIENTO REPRODUCTIVO DEL SEMEN REFRIGERADO Y CONGELADO%2FDESCONGELADO DE PORCINO Y BOVINO MEDIANTE EL USO DE LA FOTOESTIMULACION/" , "dc.relation.projectID": "info:eu-repo/grantAgreement/MINECO//RYC-2014-15581/ES/RYC-2014-15581/" , "dc.type.version": "info:eu-repo/semantics/publishedVersion" , "dc.identifier.doi": "https://doi.org/10.1038/s42003-022-03954-0" , "dc.identifier.idgrec": "035679" , "dc.contributor.funder": "Agencia Estatal de Investigación" , "dc.contributor.funder": "Ministerio de Economía y Competitividad (Espanya)" , "dc.type.peerreviewed": "peer-reviewed" , "dc.relation.FundingProgramme": "Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016" , "dc.relation.FundingProgramme": "Dirección General de Investigación Científica y Técnica" , "dc.relation.ProjectAcronym": "MEJORA DEL RENDIMIENTO REPRODUCTIVO DEL SEMEN REFRIGERADO Y CONGELADO/DESCONGELADO DE PORCINO Y BOVINO MEDIANTE EL USO DE LA FOTOESTIMULACION" , "dc.relation.ProjectAcronym": "RYC-2014-15581" , "dc.identifier.eissn": "2399-3642" }