{ "dc.contributor.author": "García Marcos, Eloy" , "dc.contributor.author": "Diaz Montesdeoca, Oliver" , "dc.contributor.author": "Martí Marly, Robert" , "dc.contributor.author": "Díez Donoso, Santiago" , "dc.contributor.author": "Gubern Mérida, Albert" , "dc.contributor.author": "Sentís, Melcior" , "dc.contributor.author": "Martí Bonmatí, Joan" , "dc.contributor.author": "Oliver i Malagelada, Arnau" , "dc.date.accessioned": "2017-10-20T07:15:31Z" , "dc.date.available": "2017-10-20T07:15:31Z" , "dc.date.issued": "2017-08-01" , "dc.identifier.issn": "0720-048X" , "dc.identifier.uri": "http://hdl.handle.net/10256/14462" , "dc.description.abstract": "The aim of this paper is to evaluate the spatial glandular volumetric tissue distribution as well as the density measures provided by Volpara™ using a dataset composed of repeated pairs of mammograms, where each pair was acquired in a short time frame and in a slightly changed position of the breast. Materials and methods We conducted a retrospective analysis of 99 pairs of repeatedly acquired full-field digital mammograms from 99 different patients. The commercial software Volpara™ Density Maps (Volpara Solutions, Wellington, New Zealand) is used to estimate both the global and the local glandular tissue distribution in each image. The global measures provided by Volpara™, such as breast volume, volume of glandular tissue, and volumetric breast density are compared between the two acquisitions. The evaluation of the local glandular information is performed using histogram similarity metrics, such as intersection and correlation, and local measures, such as statistics from the difference image and local gradient correlation measures. Results Global measures showed a high correlation (breast volume R = 0.99, volume of glandular tissue R = 0.94, and volumetric breast density R = 0.96) regardless the anode/filter material. Similarly, histogram intersection and correlation metric showed that, for each pair, the images share a high degree of information. Regarding the local distribution of glandular tissue, small changes in the angle of view do not yield significant differences in the glandular pattern, whilst changes in the breast thickness between both acquisition affect the spatial parenchymal distribution. Conclusions This study indicates that Volpara™ Density Maps is reliable in estimating the local glandular tissue distribution and can be used for its assessment and follow-up. Volpara™ Density Maps is robust to small variations of the acquisition angle and to the beam energy, although divergences arise due to different breast compression conditions" , "dc.description.sponsorship": "This work was partially funded by the Ministry of Economy and Competitiveness of Spain grant under project reference DPI2015-68442-R and by Universitat de Girona by UdG grant MPCUdG2016/022. Eloy Garcıa holds a FPI grant BES-2013-065314. Oliver Diaz is funded by the SCARtool project (H2020-MSCA-IF-2014, reference 657875), a research funded by the European Union within the Marie Sklodowska-Curie Innovative Training Networks" , "dc.format.mimetype": "application/pdf" , "dc.language.iso": "eng" , "dc.publisher": "Elsevier" , "dc.relation": "MINECO/PE 2016-2018/DPI2015-68442-R" , "dc.relation.isformatof": "Reproducció digital del document publicat a: https://doi.org/10.1016/j.ejrad.2017.05.033" , "dc.relation.ispartof": "© European Journal of Radiology, 2017, vol. 93, p. 121-127" , "dc.relation.ispartofseries": "Articles publicats (D-ATC)" , "dc.rights": "Tots els drets reservats" , "dc.subject": "Mama -- Radiografia" , "dc.subject": "Breast -- Radiography" , "dc.subject": "Imatges -- Anàlisi" , "dc.subject": "Image analysis" , "dc.subject": "Imatgeria mèdica" , "dc.subject": "Imaging systems in medicine" , "dc.subject": "Mama -- Càncer -- Imatgeria" , "dc.subject": "Breast -- Cancer -- Imaging" , "dc.subject": "Polímers -- Biodegradació" , "dc.title": "Local breast density assessment using reacquired mammographic images" , "dc.type": "info:eu-repo/semantics/article" , "dc.rights.accessRights": "info:eu-repo/semantics/embargoedAccess" , "dc.embargo.terms": "Cap" , "dc.relation.projectID": "info:eu-repo/grantAgreement/EC/H2020/657875" , "dc.type.version": "info:eu-repo/semantics/publishedVersion" , "dc.identifier.doi": "https://doi.org/10.1016/j.ejrad.2017.05.033" , "dc.identifier.idgrec": "026928" , "dc.contributor.funder": "Ministerio de Economía y Competitividad (Espanya)" }