Optimal latent period in a bacteriophage population model structured by infection-age
dc.contributor.author
dc.date.accessioned
2014-03-24T11:02:27Z
dc.date.available
2014-03-24T11:02:27Z
dc.date.issued
2011
dc.identifier.issn
0218-2025
dc.identifier.uri
dc.description.abstract
We study the lysis timing of a bacteriophage population by means of a continuously infection-age-structured population dynamics model. The features of the model are the infection process of bacteria, the death process, and the lysis process which means the replication of bacteriophage viruses inside bacteria and the destruction of them. The time till lysis (or latent period) is assumed to have an arbitrary distribution. We have carried out an optimization procedure, and we have found that the latent period corresponding to maximal fitness (i.e. maximal growth rate of the bacteriophage population) is of fixed length. We also study the dependence of the optimal latent period on the amount of susceptible bacteria and the number of virions released by a single infection. Finally, the evolutionarily stable strategy of the latent period is also determined as a fixed period taking into account that super-infections are not considered
dc.format.mimetype
application/pdf
dc.language.iso
eng
dc.publisher
World Scientific Publishing
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Versió preprint del document publicat a: http://dx.doi.org/10.1142/S0218202511005180
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© Mathematical Models and Methods in Applied Sciences, 2011, vol. 21, p. 693
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Articles publicats (D-IMA)
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Tots els drets reservats
dc.subject
dc.title
Optimal latent period in a bacteriophage population model structured by infection-age
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/openAccess
dc.embargo.terms
Cap
dc.type.version
info:eu-repo/semantics/submittedVersion
dc.identifier.doi
dc.identifier.idgrec
015086
dc.identifier.eissn
1793-6314