Body Skin laxity treatment using hybrid cooperative complexes of hyaluronans: a real-world data evaluation of patient-reported satisfaction

Abstract

Background: The Profhilo® Body Kit is indicated for the treatment of skin laxity of the body and consists of the Profhilo® Body hyaluronic acid (HA) injectable, the HA-containing Profhilo® Figura Body Patch and the Profhilo® Figura Body Cream. Aim: To assess real-world data of patient-reported satisfaction associated with the Profhilo® Body Kit treatment for skin laxity of the inner arms, abdomen, décolleté, and knees. Methods: The Profhilo® Body injection and Profhilo® Figura Body Patch were administered on Day 0 and Day 30; the Profhilo® Figura Body Cream was applied daily between the two injections. Surveys were conducted using a web app tool (Day 0, Day 30 and 30-days after second injection) and assessed patient discomfort (Visual Analogue Scale), treatment effectiveness, and psychological and social function (effects assessed using four categories: 'not at all', 'a little', 'a lot' and 'very much'). Results: Patients (N=50; 83% female) were treated at centres in Italy (n=35) and in the Netherlands (n=15). Most patients had no/mild procedure-related pain (86%) and the majority of post-injection symptoms disappeared within 48 hours (94%). Over 80% of patients reported that treatment benefited them 'a lot' and 'very much', with improvements in skin laxity, skin hydration and skin firmness/tone; beneficial treatment effects were also reported for enhancement of body image, appearance and improvement in relationships. Discussion and Conclusions: These results indicate a high-level of patient-reported satisfaction due to the Profhilo® Body Kit and this contributes to the growing body of evidence supporting the use of Profhilo® Body for the treatment of skin laxity