Editorial: Special Issue: Vaccines against Antibiotic-Resistant Bacteria: From Bench to Bedside

Abstract

The emergence and global dissemination of bacterial strains from numerous species with resistance to multiple antibiotic classes has increased in recent years, both in the healthcare and the community setting. Currently, antimicrobial resistance is a major threat to global public health, which is projected to worsen in the years to come. To overcome this situation, in addition to existing approaches, novel strategies to fight against the most concerning species, including both Gram-positive and Gram-negative bacteria, are required. In this context, vaccination has been proven as an effective approach for preventing and reducing bacterial infections that cause diphtheria, tetanus, meningitis, bubonic plague, and anthrax, among others. Therefore, according to the World Health Organization’s recommendations, the research, development, and implementation of vaccines are particularly necessary, since vaccination can help to limit the spread of antibiotic resistance. In this context, this Special Issue comprises four original research studies and a review, elucidating the potential for vaccines to contribute to reducing the burden of disease of infections caused by antibiotic-resistant bacteria