DUGiDocsKOtBu Mediated Alcohol Dehydrogenation Strategy: Synthesis of 2-Aryl Quinazolinones
dc.contributor.author
dc.date.accessioned
2024-04-03T07:19:03Z
dc.date.available
2024-04-03T07:19:03Z
dc.date.issued
2024-03-18
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dc.description.abstract
Herein we report an atom-economical, transition metal-free method for synthesizing 2-aryl quinazolinones through a cascade annulation of 2-amino benzamide and benzyl alcohol. The reaction proceeds via KOtBu-mediated acceptorless alcohol dehydrogenation pathways. The procedure tolerates a wide variety of functional groups and provides a convenient method for the synthesis of 2-aryl quinazolinones. Mechanistic insights by experiments and DFT calculations lead to unveil the reaction mechanism
dc.description.sponsorship
Science and Engineering Research Board. Grant Number: SRG/2020/002161; NIT Calicut; Serra Húnter Fellow; ICREA Academia Prize 2019; Spanish Ministerio de Ciencia e Innovación. Grant Number: PID2021-127423NB-I00 and Generalitat de Catalunya. Grant Number: 2021SGR623
Open Access funding provided thanks to the CRUE-CSIC agreement with Wiley
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application/pdf
dc.language.iso
eng
dc.publisher
Wiley
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PID2021-127423NB-I00
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Reproducció digital del document publicat a: https://doi.org/10.1002/slct.202400468
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ChemistrySelect, 2024, vol. 9, núm. 11, p. e202400468
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Articles publicats (D-Q)
dc.rights
Attribution 4.0 International
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dc.subject
dc.title
KOtBu Mediated Alcohol Dehydrogenation Strategy: Synthesis of 2-Aryl Quinazolinones
dc.type
info:eu-repo/semantics/article
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info:eu-repo/semantics/openAccess
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info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2021-127423NB-I00/ES/CATALISIS PREDICTIVA PARA CAMBIAR EL ODEN SECUENCIAL ENTRE EXPERIMENTOS I CALCULOS/
dc.type.version
info:eu-repo/semantics/acceptedVersion
dc.identifier.doi
dc.contributor.funder
dc.type.peerreviewed
peer-reviewed
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dc.identifier.eissn
2365-6549