DUGiDocsDeleterious mutations of MC1R in guinea pig
dc.contributor.author
dc.date.accessioned
2024-01-29T15:51:26Z
dc.date.available
2024-01-29T15:51:26Z
dc.date.issued
2018-10
dc.identifier.issn
0268-9146
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dc.description.abstract
In guinea pigs (Cavia porcellus) the Extension locus has three alleles E > ep > e related to black eumelanic, bicolor and brown phaeomelanic phenotypes, respectively. This locus has been molecularly characterized as the melanocortin receptor (MC1R) gene in other animals and it codes for a G-coupled receptor that regulates the synthesis of eumelanins and phaeomelanins. Genetic changes causing the inactivation of the receptor lead to the exclusive production of yellow-brown phaeomelanins, while the constitutive activation is linked to the synthesis of black eumelanins. In this context, the objective of this study is to molecularly characterize MC1R and its variations in guinea pig, and to assess their associations with the coat colors of the Extension locus
dc.format.extent
2 p.
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application/pdf
dc.language.iso
eng
dc.publisher
Wiley
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Versió postprint del document publicat a: https://doi.org/10.1111/age.12708
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© Animal Genetics, 2018, vol. 49, núm. 5, p. 498-499
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Articles publicats (D-B)
dc.rights
Tots els drets reservats
dc.source
Vidal i Fàbrega, Oriol 2018 Deleterious mutations of MC1R in guinea pig. Animal Genetics 49 5 498 499
dc.title
Deleterious mutations of MC1R in guinea pig
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/openAccess
dc.type.version
info:eu-repo/semantics/acceptedVersion
dc.identifier.doi
dc.identifier.idgrec
029690
dc.type.peerreviewed
peer-reviewed
dc.identifier.eissn
1365-2052