Postmortem diagnosis of Takotsubo syndrome on autoptic findings: is it reliable? A systematic review
dc.contributor.author
dc.date.accessioned
2024-01-22T12:44:11Z
dc.date.available
2024-01-22T12:44:11Z
dc.date.issued
2023-07-25
dc.identifier.issn
1054-8807
dc.identifier.uri
dc.description.abstract
Takotsubo syndrome (TTS) is a cardiac syndrome characterized by transient left ventricular systolic dysfunction in the absence of significant obstructive coronary artery disease. At the autopsy, its diagnosis is often challenging, since it is generally thought that it relates to no characteristic macroscopic or microscopic findings. In order to verify this last statement, we performed a systematic review of the literature following Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement (PRISMA) criteria. To the best of our knowledge, it is the first systematic review addressing this issue. We identified recurring but not pathognomonic (microscopic) features of TTS: contraction band necrosis and non-specific inflammatory changes (e.g., interstitial infiltrates of mononuclear lymphocytes and macrophages) typically in the absence of microscopic findings typical of acute myocardial infarction. In cases of TTS-related sudden death, careful evaluation of anamnesis, autopsy data and post-mortem genetic results (to exclude other causes) should be considered to overcome the complexity of these cases
dc.format.mimetype
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier
dc.relation.isformatof
Reproducció digital del document publicat a: https://doi.org/10.1016/j.carpath.2023.107543
dc.relation.ispartof
Cardiovascular Pathology, 2023, vol. 65, art.núm.107543
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Articles publicats (D-CM)
dc.rights
Reconeixement-NoComercial-SenseObraDerivada 4.0 Internacional
dc.rights.uri
dc.source
Grassi, Simone Campuzano Larrea, Oscar Cazzato, Francesca Coll Vidal, Mònica Puggioni, Alessandra Zedda, Massimo Arena, Vincenzo Iglesias, Anna Sarquella Brugada, Geòrgia Pinchi, Vilma Brugada, Ramon Oliva, Antonio 2023 Postmortem diagnosis of Takotsubo syndrome on autoptic findings: is it reliable? A systematic review. Cardiovascular Pathology 65 art.núm.107543
dc.subject
dc.title
Postmortem diagnosis of Takotsubo syndrome on autoptic findings: is it reliable? A systematic review
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/openAccess
dc.type.version
info:eu-repo/semantics/publishedVersion
dc.identifier.doi
dc.identifier.idgrec
037609
dc.type.peerreviewed
peer-reviewed
dc.identifier.eissn
1879-1336