Synthetic Peptides against Plant Pathogenic Bacteria
dc.contributor.author
dc.date.accessioned
2022-09-16T09:54:48Z
dc.date.available
2022-09-16T09:54:48Z
dc.date.issued
2022-09-03
dc.identifier.uri
dc.description.abstract
The control of plant diseases caused by bacteria that seriously compromise crop productivity around the world is still one of the most important challenges in food security. Integrated approaches for disease control generally lack plant protection products with high efficacy and low environmental and health adverse effects. Functional peptides, either from natural sources or synthetic, are considered as novel candidates to develop biopesticides. Synthetic peptides can be obtained based on the structure of natural compounds or de novo designed, considering the features of antimicrobial peptides. The advantage of this approach is that analogues can be conveniently prepared, enabling the identification of sequences with improved biological properties. Several peptide libraries have been designed and synthetized, and the best sequences showed strong bactericidal activity against important plant pathogenic bacteria, with a good profile of biodegradability and low toxicity. Among these sequences, there are bacteriolytic or antibiofilm peptides that work against the target bacteria, plant defense elicitor peptides, and multifunctional peptides that display several of these properties. Here, we report the research performed by our groups during the last twenty years, as well as our ongoing work. We also highlight those peptides that can be used as candidates to develop novel biopesticides, and the main challenges and prospects
dc.description.sponsorship
This research has been funded in the last five years by different grants from Spain, including those by the Ministerio de Ciencia, Innovación y Universidades RTI2018-099410-B-C21; RTI2018-099410-B-C22; and ERTA INIA 2017-00004-C06-03 and from the European Union H2020 Program XF-Actors cod. 727987
dc.format.mimetype
application/pdf
dc.language.iso
eng
dc.publisher
MDPI (Multidisciplinary Digital Publishing Institute)
dc.relation
RTI2018-099410-B-C21
RTI2018-099410-B-C22
dc.relation.isformatof
Reproducció digital del document publicat a: https://doi.org/10.3390/microorganisms10091784
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Microorganisms, 2022, vol. 10, núm. 9, p. 1784
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Articles publicats (D-EQATA)
dc.rights
Attribution 4.0 International
dc.rights.uri
dc.subject
dc.title
Synthetic Peptides against Plant Pathogenic Bacteria
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/openAccess
dc.relation.projectID
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-099410-B-C21/ES/PEPTIDOS DIRIGIDOS A DIANAS Y PROCESOS CLAVE PARA EL CONTROL DE XYLELLA FASTIDIOSA/
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-099410-B-C22/ES/PEPTIDOS DIRIGIDOS A DIANAS Y PROCESOS CLAVE PARA EL CONTROL DE XYLELLA FASTIDIOSA. DISEÑO, SINTESIS Y OPTIMIZACION/
dc.type.version
info:eu-repo/semantics/publishedVersion
dc.identifier.doi
dc.contributor.funder
dc.type.peerreviewed
peer-reviewed
dc.relation.FundingProgramme
dc.relation.ProjectAcronym
dc.identifier.eissn
2076-2607