DUGiDocsGenome analysis of a new Escherichia phage vB_EcoM_C2-3 with lytic activity against multidrug-resistant Escherichia coli
dc.contributor.author
dc.date.accessioned
2022-01-27T08:28:58Z
dc.date.available
2022-01-27T08:28:58Z
dc.date.issued
2022-01-02
dc.identifier.issn
0168-1702
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dc.description.abstract
In this study, we present the complete, annotated genome of a new member of the Tequatrovirus (T4-like) genus, Escherichia phage vB_EcoM_C2–3. This phage has an isometric head (92 nm in diameter) and a contractile tail (114 nm in length). Its genome consists of a linear, double-stranded DNA of 167,069bp with an average G+C content of 35.3%. There are 267 predicted genes, of which 125 encode functional proteins, including those for DNA replication, transcription and packaging, phage morphogenesis and cell lysis. Neither genes involved in the regulation of lysogeny nor antibiotic resistance genes were identified. Based on our results, its genomic features provide valuable insights into the use of a potential biocontrol agent, as Escherichia phage vB_EcoM_C2–3 exhibited lytic activity against E. coli, including multidrug-resistant strains
dc.description.sponsorship
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 792686”.This work was also supported by the Generalitat de Catalunya (ICRA-ENV 2017 SGR 1124), the CERCA Program of the Catalan Government, and by a New Lecturer Research Grant from the Society for Applied Microbiology. The authors thank Dr. Kaczorowski for providing us with the reference E. coli strain. EGV thanks the National Council for Science and Technology (CONACYT, Mexico) for the postdoctoral fellowship (CVU no. 441304)
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application/pdf
dc.language.iso
eng
dc.publisher
Elsevier
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Versió postprint del document publicat a: https://doi.org/10.1016/j.virusres.2021.198623
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© Virus Research, 2022, vol. 307, art.núm. 198623
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Articles publicats (D-B)
dc.rights
Attribution-NonCommercial-NoDerivatives 4.0 International
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dc.subject
dc.title
Genome analysis of a new Escherichia phage vB_EcoM_C2-3 with lytic activity against multidrug-resistant Escherichia coli
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/openAccess
dc.date.embargoEndDate
info:eu-repo/date/embargoEnd/2023-01-02
dc.relation.projectID
info:eu-repo/grantAgreement/EC/H2020/792686/EU/Exploring the contribution of bacteriophages to the emergence and spread of antibiotic resistance in environmental settings/ENVIROSTOME
dc.type.version
info:eu-repo/semantics/acceptedVersion
dc.identifier.doi
dc.identifier.idgrec
034494
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dc.type.peerreviewed
peer-reviewed
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