Circulating Non-Esterified Fatty Acids as Biomarkers for Fat Content and Composition in Pigs
dc.contributor.author
dc.date.accessioned
2021-11-22T13:14:15Z
dc.date.available
2021-11-22T13:14:15Z
dc.date.issued
2021-02-03
dc.identifier.uri
dc.description.abstract
Circulating non-esterified fatty acids (NEFA) can reflect the composition of dietary fat or adipose tissues depending on the fasting conditions. Therefore, circulating NEFA may be valuable as biomarkers for meat quality traits, such as intramuscular fat content and fatty acid composition in finishing pigs. Genetic variants that regulate lipid metabolism can also modulate the circulating NEFA. We conducted an experiment with 150 heavy Duroc pigs to evaluate fluctuations in the circulating NEFA composition due to age, fasting duration and two genetic polymorphisms, one in the leptin receptor (LEPR; rs709596309) and one in the stearoyl-CoA desaturase (SCD; rs80912566) gene. Circulating NEFA were more saturated and less monounsaturated than the subcutaneous and intramuscular adipose tissues. Absolute circulating NEFA content was more influenced by fasting duration than age. The SCD polymorphism did not impact NEFA content or composition. The LEPR polymorphism affected the content but not the fatty acid composition. Circulating oleic acid NEFA content after a short fasting was positively correlated with intramuscular fat content and, after a long fasting, with intramuscular oleic acid content. We conclude that circulating NEFA reflect environmental and genetic metabolic changes but are of limited value as biomarkers for intramuscular fat content and fatty acid composition
dc.description.sponsorship
This Research was founded by the Spanish Ministry of Economy and Competitiveness and the European Union Regional Development Funds (grants AGL2012-33529, AGL2015-65846-R, and RTI2018-101346-B-I00)
dc.format.mimetype
application/pdf
dc.language.iso
eng
dc.publisher
MDPI (Multidisciplinary Digital Publishing Institute)
dc.relation.isformatof
Reproducció digital del document publicat a: https://doi.org/10.3390/ani11020386
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Animals, 2021, vol. 11, núm. 2, p. 386
dc.relation.ispartofseries
Articles publicats (D-EQATA)
dc.rights
Attribution 4.0 International
dc.rights.uri
dc.title
Circulating Non-Esterified Fatty Acids as Biomarkers for Fat Content and Composition in Pigs
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/openAccess
dc.type.version
info:eu-repo/semantics/publishedVersion
dc.identifier.doi
dc.identifier.idgrec
032812
dc.type.peerreviewed
peer-reviewed
dc.identifier.eissn
2076-2615