Instituto de Salud Carlos III, Grant/Award Numbers: PI11/01889, PI08/1770, PI08/0533, PI08/1359, PS09/00773, PS09/01286, PS09/01903, PS09/02078, PS09/01662, PI11/02213, PI12/00488, PI12/01270; Fundación Marqués de Valdecilla, Grant/Award Number: API 10/09; ICGC International Cancer Genome Consortium CLL (The ICGC CLL‐Genome Project is funded by Spanish Ministerio de Economía y Competitividad (MINECO) through the Instituto de Salud Carlos III (ISCIII) and Red Temática de Investigación del Cáncer (RTICC) del ISCIII), Grant/Award Number: RD12/0036/0036; Junta de Castilla y León, Grant/Award Number: LE22A10‐2; Consejería de Salud of the Junta de Andalucía, Grant/Award Numbers: PI‐0571‐2009, PI‐0306‐2011, salud201200057018tra; Conselleria de Sanitat of the Generalitat Valenciana, Grant/Award Number: AP_061/10; Recercaixa, Grant/Award Number: 2010ACUP 00310; Regional Government of the Basque Country; Consejería de Sanidad de la Región de Murcia; European Commission, Grant/Award Number: FOOD‐CT‐2006‐036224‐HIWATE; Spanish Association Against Cancer (AECC) Scientific Foundation; Catalan Government‐Agency for Management of University and Research Grants (AGAUR), Grant/Award Numbers: 2017SGR723, 2014SGR850; Fundación Caja de Ahorros de Asturias and by the University of Oviedo; Spanish Ministry of Science and Innovation through the “Centro de Excelencia Severo Ochoa 2019‐2023” Program, Grant/Award Number: CEX2018‐000806‐S; Generalitat de Catalunya through the CERCA Program