Seminal plasma anti-Müllerian hormone: a potential AI-boar fertility biomarker?
dc.contributor.author
dc.date.accessioned
2020-04-15T09:35:33Z
dc.date.available
2020-04-15T09:35:34Z
dc.date.issued
2020-04-10
dc.identifier.uri
dc.description.abstract
The anti-Müllerian hormone (AMH), a Sertoli cell-secreted glycoprotein that is present in seminal plasma (SP), is considered as a marker of spermatogenesis in humans. This study aimed to evaluate the presence of this hormone in boar SP, together with its putative relationship with sperm quality, function, and in vivo fertility parameters in liquid-stored semen samples. The concentration of SP-AMH was assessed in 126 ejaculates from artificial insemination (AI)-boars (n = 92) while using a commercial Enzyme-Linked ImmunoSorbent Assay (ELISA) kit with monoclonal antibodies specific for Sus scrofa AMH (CEA228Po, Cloud-clone). Sperm quality (concentration, motility, viability, and acrosome damage) and functionality (membrane lipid disorder and intracellular H2O2 generation) were assessed in semen samples at 0 and 72 h of liquid-storage. In addition, fertility parameters from 3113 sows inseminated with the AI-boars were recorded in terms of farrowing rate, litter size, number of stillbirths per litter, and the duration of pregnancy over a 12-month period. The results revealed that the SP-AMH concentration varied widely among boar ejaculates, with no differences among breeds. Moreover, the SP-AMH concentration proved to be a good predictive biomarker for sperm concentration (p ˂ 0.05), but poor for other sperm quality, functionality, and in vivo fertility parameters of liquid-stored semen samples from AI-boars
dc.description.sponsorship
This research was funded by European Commission (H2020-MSCA-IF-79212); Ministry of Science, Innovation and Universities, Spain (RYC-2014-15581, AGL2017-88329-R, FJCI-2017-31689 and PRE2018-083488);
and Regional Government of Catalonia, Spain (2017-SGR-1229)
dc.format.mimetype
application/pdf
dc.language.iso
eng
dc.publisher
MDPI (Multidisciplinary Digital Publishing Institute)
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Reproducció digital del document publicat a: https://doi.org/10.3390/biology9040078
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Biology, 2020, vol. 9, núm. 4, p. 78
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Articles publicats (D-B)
dc.rights
Attribution 4.0 International
dc.rights.uri
dc.source
Barranco, Isabel Fernández Fuertes, Beatriz Padilla, Lorena Delgado Bermúdez, Ariadna Tvarijonaviciute, Asta Yeste Oliveras, Marc 2020 Seminal plasma anti-Müllerian hormone: a potential AI-boar fertility biomarker? Biology 9 4 78
dc.subject
dc.title
Seminal plasma anti-Müllerian hormone: a potential AI-boar fertility biomarker?
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/openAccess
dc.relation.projectID
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2017-88329-R/ES/MEJORA DEL RENDIMIENTO REPRODUCTIVO DEL SEMEN REFRIGERADO Y CONGELADO/DESCONGELADO DE PORCINO Y BOVINO MEDIANTE EL USO DE LA FOTOESTIMULACION/
info:eu-repo/grantAgreement/MINECO//RYC-2014-15581/ES/RYC-2014-15581/
dc.type.version
info:eu-repo/semantics/publishedVersion
dc.identifier.doi
dc.identifier.idgrec
031274
dc.contributor.funder
dc.type.peerreviewed
peer-reviewed
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dc.relation.ProjectAcronym
dc.identifier.eissn
2079-7737