The value of targeted MRI-US fusion biopsy in men with prior negative biopsy for prostate cancer detection
dc.contributor
dc.contributor.author
dc.contributor.other
dc.date.accessioned
2019-06-11T07:46:10Z
dc.date.available
2019-06-11T07:46:10Z
dc.date.issued
2019-01
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dc.description.abstract
Background
Prostate cancer (PCa) is very prevalent among men, but with low mortality rates. This is mainly
due to the high detection of indolent lesions that are more frequent than aggressive ones.
The traditional strategy for PCa detection until recently has been the blinded random biopsies
of the entire gland, called systematic biopsy (SB), by transrectal ultrasounds (TRUS) guidance.
Lately, multiparametric magnetic resonance imaging (mpMRI) has been becoming a clue tool in
PCa detection. Nowadays, the recommendation in men with previous negative biopsy and PCa
suspicion is to perform magnetic resonance-guided biopsy (MRGB), in addition to SB, as the
diagnostic procedure. The application of mpMRI in men without previous biopsy is not that
supported, even though is starting to grow. There are predominantly 3 MRGB techniques.
Objective
To assess whether MRGB by magnetic resonance imaging-ultrasounds (MRI-US) fusion
technique improves the detection rate of clinically significant PCa over SB to improve the
management of prostate cancer.
Design and methods
In this cross-sectional single centre study, both biopsy techniques (MRGB by fusion technique
and SB) will be performed to patients with a PCa suspicion and a previous negative biopsy, if the
MRI is suggestive of PCa. Men whose MRI results are not suggestive of PCa will not be offered
biopsy. A 12-core SB guided by TRUS will be carried out firstly before the MRGB, without any
information of the MRI. The results of each technique will be compared
dc.format.mimetype
application/pdf
dc.language.iso
eng
dc.relation.ispartofseries
Medicina (TFG)
dc.rights
Attribution-NonCommercial-NoDerivatives 4.0 International
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dc.subject
dc.title
The value of targeted MRI-US fusion biopsy in men with prior negative biopsy for prostate cancer detection
dc.type
info:eu-repo/semantics/bachelorThesis
dc.rights.accessRights
info:eu-repo/semantics/openAccess
dc.audience.educationlevel
Estudis de grau