A CBR-based bolus recommender system for type 1 diabetes

Abstract

People with type 1 diabetes mellitus usually need to administer bolus insulin before each meal to keep the blood glucose level in the target glycaemic range. However, the factors involved in the calculation of the appropriate dose can change due to multiple factors and with an unknown relation. This may increase the error in the bolus calculation, and therefore, increase the chances of hypoglycaemia and hyperglycaemia. This paper proposes a bolus recommender system based on case based reasoning developed under project PEPPER, with the objective of recommending personalised and adaptive bolus doses. The system has been tested with in silico adults with UVA/PADOVA T1DM simulator. Results show that the use of the proposed bolus recommender system increases the percentage of time in the target glycaemic range