Population structure of eleven Spanish ovine breeds and detection of selective sweeps with BayeScan and hapFLK
dc.contributor.author
dc.date.accessioned
2017-05-22T12:10:04Z
dc.date.available
2017-05-22T12:10:04Z
dc.date.issued
2016-06-07
dc.identifier.issn
2045-2322
dc.identifier.uri
dc.description.abstract
The goals of the current work were to analyse the population structure of 11 Spanish ovine breeds and to detect genomic regions that may have been targeted by selection. A total of 141 individuals were genotyped with the Infinium 50 K Ovine SNP BeadChip (Illumina). We combined this dataset with Spanish ovine data previously reported by the International Sheep Genomics Consortium (N = 229). Multidimensional scaling and Admixture analyses revealed that Canaria de Pelo and, to a lesser extent, Roja Mallorquina, Latxa and Churra are clearly differentiated populations, while the remaining seven breeds (Ojalada, Castellana, Gallega, Xisqueta, Ripollesa, Rasa Aragonesa and Segureña) share a similar genetic background. Performance of a genome scan with BayeScan and hapFLK allowed us identifying three genomic regions that are consistently detected with both methods i.e. Oar3 (150–154 Mb), Oar6 (4–49 Mb) and Oar13 (68–74 Mb). Neighbor-joining trees based on polymorphisms mapping to these three selective sweeps did not show a clustering of breeds according to their predominant productive specialization (except the local tree based on Oar13 SNPs). Such cryptic signatures of selection have been also found in the bovine genome, posing a considerable challenge to understand the biological consequences of artificial selection
dc.format.mimetype
application/pdf
dc.language.iso
eng
dc.publisher
Nature Publishing Group
dc.relation.isformatof
Reproducció digital del document publicat a: http://dx.doi.org/10.1038/srep27296
dc.relation.ispartof
Scientific Reports, núm. 6, art. 27296
dc.relation.ispartofseries
Articles publicats (D-B)
dc.rights
Attribution 4.0 Spain
dc.rights.uri
dc.subject
dc.title
Population structure of eleven Spanish ovine breeds and detection of selective sweeps with BayeScan and hapFLK
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/openAccess
dc.embargo.terms
Cap
dc.type.version
info:eu-repo/semantics/publishedVersion
dc.identifier.doi
dc.identifier.idgrec
026076