DUGiDocsSolid-Phase Synthesis of Cyclic Depsipeptides Containing a Tyrosine Phenyl Ester Bond
dc.contributor.author
dc.date.accessioned
2017-02-28T08:54:21Z
dc.date.available
2017-02-28T08:54:21Z
dc.date.issued
2016-08-19
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1523-7060
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dc.description.abstract
The first solid-phase strategy for the synthesis of cyclic depsipeptides containing a phenyl ester linkage in their structure is described. The key steps of the synthesis were the formation of the phenyl ester bond and the on-resin head-to-side-chain cyclization. The amino acid configuration significantly influenced the formation and the stability of the cyclic depsipeptides. The presence of a l-Tyr1 and a d-Tyr7 led to the most stable sequences
dc.description.sponsorship
This work was financed by Grant AGL2012-39880-C02-02
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application/pdf
dc.language.iso
eng
dc.publisher
American Chemical Society (ACS)
dc.relation
info:eu-repo/grantAgreement/MINECO//AGL2012-39880-C02-02/ES/NUEVAS ESTRATEGIAS DE CONTROL DEL FUEGO BACTERIANO. PEPTIDOS SINTETICOS ESTIMULADORES DE DEFENSA EN EL HUESPED/
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Reproducció digital del document publicat a: http://dx.doi.org/10.1021/acs.orglett.6b02281
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© Organic Letters, 2016, vol. 18, núm. 16, p. 4140-4143
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Articles publicats (D-Q)
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Tots els drets reservats
dc.title
Solid-Phase Synthesis of Cyclic Depsipeptides Containing a Tyrosine Phenyl Ester Bond
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/embargoedAccess
dc.embargo.terms
Cap
dc.date.embargoEndDate
info:eu-repo/date/embargoEnd/2026-01-01
dc.type.version
info:eu-repo/semantics/publishedVersion
dc.identifier.doi
dc.identifier.idgrec
025495
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dc.relation.ProjectAcronym
dc.identifier.eissn
1523-7052