Sentinel lymph node in endometrial cancer: validation of the selective sentinel lymph node biopsy technique

Abstract

BACKGROUND: Surgical staging of the endometrial cancer includes lymphadenectomy. Lymphadenectomy is associated with high earlier morbidity. Though, there is still an inability to predict which patients have lymph nodes affected and would benefit from lymphadenectomy, it continues to be the only accurate way to provide the lymphatic status of the disease, prognosis and the needing of adjuvant treatment to the patient. Sentinel lymph node mapping is a promising technique to validate and apply in the routine performance to avoid the lymphadenectomy to the patients that do not need it. AIM: The goal of the study is to evaluate the validation of the selective sentinel lymph node biopsy technique in endometrial cancer in Hospital Universitari Dr. Josep Trueta of Girona, including sensitivity, specificity and negative predictive value. METHODS: A cross-sectional design carried out within Gynaecology Oncologic Unit at Hospital Universitari Dr. Josep Trueta in Girona, in a period of time of three years and four months. PARTICIPANTS: A total of 95 patients with EC diagnosis will be included in the study