Is saliva a potential biomarker of arsenic exposure? A case-control study in West Bengal, India
dc.contributor.author
dc.date.accessioned
2016-01-25T13:39:08Z
dc.date.available
2016-01-25T13:39:08Z
dc.date.issued
2013
dc.identifier.issn
0013-936X
dc.identifier.uri
dc.description.abstract
Saliva is a biological fluid that has not been used extensively as a biomonitoring tool in epidemiological studies. This study presents the arsenic (As) concentrations in saliva and urine samples collected from populations of West Bengal, India who had been previously exposed to high As levels in their drinking water. We found a significant (p < 0.05) association between the Log transformed Daily Ingestion of As (μg day-1) and the As concentration in saliva (r = 0.68). Additionally, As concentration of saliva and urine also had a significant positive correlation (r = 0.60, p < 0.05). Male participants, smokers, and cases of skin lesion were independently and significantly associated with an increase in salivary As. Thus our findings show that saliva is a useful biomarker of As exposure in the study population. The study also advocates that measurement of the forms of As in saliva may additionally provide insight into the internal dose and any individual differences in susceptibility to As exposure
dc.description.sponsorship
The present study was funded by Trehan Foundation to the Center for South Asian Studies, University of Michigan, USA. S.B. and D.H. would like to acknowledge Erasmus Mundus External Cooperation Window (EMECW Action II) Program EURINDIA for providing their respective Doctoral Scholarship. The support from Spanish National Research Programme (CGL2010-22168-C03-03) is also duly acknowledged. The authors would also like to acknowledge the support of Mr. Prabir Kr. Das, Mr. Barun Mitra, and Dr. Nilima Ghosh for their assistance during field work. D.C. acknowledges the support of the DST-FIST and UGC-SAP program of Department of Chemistry, University of Kalyani
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application/pdf
dc.language.iso
eng
dc.publisher
American Chemical Society (ACS)
dc.relation
info:eu-repo/grantAgreement/MICINN//CGL2010-22168-C03-02/ES/APLICACION DE AGUA NO CONVENCIONAL (TRATADA-DESALADA) Y FANGOS PROCEDENTES DE DEPURADORAS URBANAS Y SU IMPACTO EN EL MEDIO ACUIFERO Y SUELOS. ETUDIOS DE CAMPOY LABORATORIO/
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Reproducció digital del document publicat a: http://dx.doi.org/10.1021/es303756s
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© Environmental Science and Technology, 2013, vol. 47, núm. 7, p. 3326-3332
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Articles publicats (D-Q)
dc.rights
Tots els drets reservats
dc.subject
dc.title
Is saliva a potential biomarker of arsenic exposure? A case-control study in West Bengal, India
dc.type
info:eu-repo/semantics/article
dc.rights.accessRights
info:eu-repo/semantics/embargoedAccess
dc.embargo.terms
Cap
dc.date.embargoEndDate
info:eu-repo/date/embargoEnd/2026-01-01
dc.type.version
info:eu-repo/semantics/publishedVersion
dc.identifier.doi
dc.identifier.idgrec
017751
dc.contributor.funder
dc.relation.ProjectAcronym
dc.identifier.eissn
1520-5851