Botulinum toxin A versus percutaneous tibial nerve stimulation in idiopathic overactive bladder: a randomized trial
dc.contributor
dc.contributor.author
dc.contributor.other
dc.date.accessioned
2017-06-20T21:40:19Z
dc.date.available
2017-06-20T21:40:19Z
dc.date.issued
2017-01
dc.identifier.uri
dc.description.abstract
The uprising number of people suffering from overactive bladder, has made evident the need of new treatments to tackle the condition in patients refractory to oral therapies. The development of third line therapies for overactive bladder, has given a lot of patients an opportunity to gain quality of life. However, these treatments can associate severe side effects, which compels us to be cautious with its prescription.
This study compares the efficacy of intradetrusor Botox ® injections and percutaneous tibial nerve stimulation measured in quality of life. In addition, an analysis of the security, convenience and cost-effective is included.
We designed multicenter clinical trial, where sequential sampling will be used to enroll a total of 234 individuals. By randomization, we will allocate the subjects in a group for botulinum toxin or a group for tibial nerve stimulation. The collaboration of seven hospitals will be required to perform this evaluation.
Our principal endpoint will be the punctuation in a disease-specific questionnaire after 12 months. The follow up will be conducted at 3, 6, 9 and 12 months with urodynamic measures, symptom reports and quality of life questionnaire
dc.format.mimetype
application/pdf
dc.language.iso
eng
dc.relation.ispartofseries
Medicina (TFG)
dc.rights
Attribution-NonCommercial-NoDerivs 3.0 Spain
dc.rights.uri
dc.subject
dc.title
Botulinum toxin A versus percutaneous tibial nerve stimulation in idiopathic overactive bladder: a randomized trial
dc.type
info:eu-repo/semantics/bachelorThesis
dc.rights.accessRights
info:eu-repo/semantics/openAccess
dc.coverage.geolocation
east=2.7970209999999724; north=41.9698449; name=Hospital de Santa Caterina
east=2.819998700000042; north=41.997504; name=Hospital Universitari de Girona Doctor Josep Trueta
east=2.23786999999993; north=41.481057; name=Hospital Germans Trias i Pujol
east=2.9536166999999978; north=42.2683545; name=Hospital de Figueres
east=3.1314876999999797; north=41.85256549999999; name=Hospital de Palamós
east=2.4685930000000553; north=42.187545; name=Hospital d’Olot i Comarcal de la Garrotxa
east=2.802170799999999; north=41.6872441; name=Hospital de Blanes
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