Evolution of retinal microvasculature abnormalities and its association with cardiovascular morbimortality

Abstract

Evolution of retinal microvasculature abnormalities (areteriovenous ratio, arteriolar caliber and venular caliber) measured by automatic retinography, in patients suffering from essential hypertension of new onset and never treated, is associated with 5 years cardiovascular morbimortality The main objective is to verify if there is an association in newly-diagnosed and never treated hypertensive patients between: Arteriovenous ratio evolution measured by automatic retinography and 5 years cardiovascular morbimortality Arteriolar caliber evolution measured by automatic retinography and 5 years cardiovascular morbimortality Venular caliber evolution measured by automatic retinography and 5 years cardiovascular morbimortality The secondary objective is to verify if there is an association between arteriovenous ratio baseline values and cardiovascular mortality The target population is composed by patients with essential hypertension of new onset and never treated, according to the ESH-ESC criteria, aged 35 to 74 years